Find Funding Opportunities for the Indiana Uplands
Regional Opportunity Initiatives (ROI) curates grant opportunities that support nonprofits, local governments, schools, and community organizations across the Indiana Uplands region. This page highlights funding aligned with regional priorities. Browse current opportunities below and follow the links provided to learn more about eligibility and application requirements.
Note: Unless otherwise indicated, ROI does not administer these grants.
Featured Grants

Community Development
Safe Streets and Roads for All Grant Funding
US Department of Transportation
$100,000 – $25,000,000
Deadline: May 26, 2026

Community Development
Historic Preservation Fund Grant Program
Indiana Department of Natural Resources
$10,000 – $75,000
Deadline: June 5, 2026
Browse Grants By Category
Arts Project Support Grants
Indiana Arts Commission
Funding: Up to $4,000
Deadline: September 3, 2026
Supports public facing, short-term arts projects or series of arts activities including performances, exhibits, arts festivals, and public art.
Media Projects Grants
National Endowment for the Humanities
Funding: $1 – $700,000
Deadline: June 25, 2026
Supports the development, production, and distribution of radio programs, podcasts, and documentary files to engage broad audiences with humanities ideas through compelling and accessible storytelling.
T-Mobile Hometown Grants
Funding: Up to $50,000
Application Cycles: Quaterly
Supports community revitalization projects that enhance public spaces, strengthen local economies, and improve quality of life in small towns.
Safe Streets and Roads for All Funding
US Department of Transportation
Funding: $100,000 – $25,000,000
Deadline: May 26, 2026
Supports planning, demonstration, and implementation projects aimed at improving safety for all road users.
Historic Preservation Fund Grant Program
Indiana Department of Natural Resources
Funding: $10,000 – $75,000
Deadline: June 5, 2026
Supports preservation, rehabilitation, or restoration activities for historic resources currently listed in the National Register of Historic Places.
Encouraging Citizen Involvement Grants
The Herb Block Foundation
Funding: $5,000 – $25,000
Deadline: June 4, 2026
Supports non-partisan citizen engagement initiatives including citizen education and increasing voter participation.
Defense Community Infrastructure Program
U.S. Department of Defense, Office of Local Defense Community Cooperation
Funding: $250,000 – $20,000,000
Deadline: June 25, 2026
Supports community infrastructure projects including projects related to transportation, schools, hospitals, or other community support facilities in communities supportive of a military installation.
Rural Microentrepreneur Program
U.S. Department of Agriculture
Funding: $50,000 – $500,000
Deadline: June 30, 2026
Provides loans and grants to Microenterprise Development Organizations to support microloans for rural microenterprise startups and growth through a Rural Microloan Revolving Fund.
Wish Local Empowerment Program
Funding: $500 – $2,000
Supports Black-owned brick-and-mortar retail businesses across the US in covering operating expenses such as workforce retention, rent, inventory, customer research, and community engagement.
Jeffris Heartland Fund
Jeffris Heartland Fund
Supports preservation projects in small towns and cities in the Midwest by covering 50% of the costs of a Historic Structure Report.
CreatINg Places Grant
Indiana Housing & Community Development Authority
Funding: $5,000 – $50,000 with 1:1 fundraising match requirement
Supports projects that activate underutilized public spaces or create new public spaces.
Community Facilities Direct Loan & Grant Program
U.S. Department of Agriculture Office of Rural Development
This program provides affordable funding to development essential community facilities in rural areas.
Community Heart & Soul Seed Grant Program
Funding: Up to $10,000 with a 1:1 cash match requirement
Provides start-up funding for resident-driven groups in small cities and towns looking to implement the Community Heart & Soul model.
Water & Waste Disposal Loan & Grant Program
U.S. Department of Agriculture Office of Rural Development
This program provides funding for clean and reliable drinking water systems, sanitary sewage disposal, sanitary solid waste disposal, and storm water drainage to households and businesses in rural areas.
AWS Imagine Grant
Amazon Web Services
Funding: Up to $200,000
Deadline: June 5, 2026
Supports registered nonprofits using cloud technology to accelerate their missions through pilot projects, proofs of concept, or expanded programs.
Grants to Support Railway Safety, Education, and Historic Preservation
North American Railway Foundation
Deadline: June 12, 2026
Supports projects that advance railway safety, efficiency, and technology and promote education about, and the preservation of, railroad history in the United States.
Agricultural Leadership Grant
CHS Foundation
Funding: $1,000 – $1,430,000
Supports programs that strengthen rural communities and prepares the next generation of agricultural education, leadership training, and career development for students from high school through early professional stages.
Seed Grants for Early Childhood Education Programs
Frances R. Dewing Foundation
Funding: $2,500 – $25,000
Deadlines: April 1, 2026 and October 1, 2026
Provides seed grant funding for new or experimental projects, including creative daycare initiatives, that have potential to create broader community or educational impact.
Principal Student Support Services Grant
School-Based Healthcare Solutions Network
Provides a fully funded mental health professional for each school campus who will deliver evidence-based mental health support services directly to students.
Children’s Book Project Program Grants
Funding: Up to $1,200 with a 2:1 match requirement
Deadlines: Every April 1 and October 1
Supports rural libraries to purchase new, quality, hardcover children’s books.
Employer Training Grant
Indiana Department of Workforce Development
Offers employers $5,000 per employee (up to $50,000) who is trained, hired, and retained for at least six months in select priority sectors.
Workforce Ready Grant
Indiana Department of Workforce Development
Program for individuals that covers the tuition and fees of qualifying certificate programs across Indiana.
Path to Pro Education Grants
Home Deport Foundation
Funding: In-kind support up to $10,000
Support is provided in the form of Home Depot gift cards that may be used to purchase tools, equipment, building materials, and supplies, or to support new or renovated training spaces for organizations offering vocational training in the construction industry.
Grants to Strengthen Public Middle School Education
All Points North Foundation
Funding: $60,000 – $100,000
Deadline: June 1, 2026
Supports projects that strengthen public middle school education and teacher training in underserved urban and rural communities.
Clean Water Act Section 319 Grants for Water Quality Improvement
Indiana Department of Environmental Management
Deadline: Notice of Intent to Apply due June 1, 2026; Application due September 1, 2026
Supports projects that address nonpoint source pollution and improve water quality across Indiana.
Labcorp Charitable Foundation Grants
Funding: $5,000 – $25,000
Supports community-based non-profit organizations advancing health, education, and well-being.
Mothers in Medicine Fund
Zorya Foundation
Funding: Up to $12,000
Provides childcare support to women working in healthcare who are mothers or primary caregivers.
These programs accept applications throughout the year:
- Labcorp Charitable Foundation Grants
- Wish Local Empowerment Program
- Mothers in Medicine Fund
- Agricultural Leadership Grant
- Water & Waste Disposal Loan & Grant Program
- Jeffris Heartland Fund
- CreatINg Places Grant
- Community Facilities Direct Loan & Grant Program
- Community Heart & Soul Seed Grant Program
- Employer Training Grant
- Workforce Ready Grant
- Children’s Book Project Grant
- Path to Pro Education Grants
Because deadlines may change, please check each program’s website for the most current information.
Grants with Upcoming Deadlines
- Highly Rural Transportation Grants — May 5, 2026
- Safe Streets and Roads for All Grants — May 26, 2026
ROI’s Grant Opportunities
Regional Opportunity Initiatives periodically offers grant opportunities that support regional collaboration, education and workforce initiatives, and community development across the Indiana Uplands.
There are no open ROI grant programs at this time. Please check back soon or subscribe to our newsletter for updates.
Need Help Finding Funding?
ROI is committed to supporting organizations in the Indiana Uplands region.
If you need assistance identifying funding opportunities or determining whether a grant is a good fit for your project, please contact Josie Smith, Grants Management Specialist, josie@regionalopportunityinc.org
Stay Updated
New funding opportunities are added regularly. Sign up for the ROI newsletter to receive updates on grants, funding announcements, and regional initiatives.
